Welcome to the Laboratory for Computational Genomics

The Laboratory for Computational Genomics (LCG) is a research center established within Washington University's Department of Computer Science and Engineering. Our mission is to develop algorithms and tools to address emerging needs in the analysis of molecular biological data, such as genomic DNA, RNA, and protein sequences and gene expression measurements.

CSE faculty associated with the LCG include:

*       Dr. Michael Brent (director)

*       Dr. Jeremy Buhler

*       Dr. Weixiong Zhang

Bioinformatics tools produced by LCG faculty include the TWINSCAN and N-SCAN gene finders; the Pairagon cDNA-genome aligner; the PPFINDER pseudogene finder; Mandala, a tool to design seeds for BLAST-like similarity search; and ILM, a tool for predicting pseudoknotted RNA secondary structures. More links to software can be found on the pages of individual lab members.

The LCG’s work is made possible by the generous research support of (among others) the National Science Foundation, the National Human Genome Research Institute, and Monsanto Corporation.

---

Last update: 2/7/2006